Publications

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2003 – 2016 GERMS-RELATED PUBLICATIONS

Peer-reviewed publications

1.  von Gottberg A, Ludewick H, Bamber S, Govind C, Sturm AW, Klugman KP.  Emergence of fluoro­quiolone-resistant Streptococcus penumoniae in a South African child in a tuberculosis treatment facility. Pediatr Infect Dis J 2003; 22:1020-1021.
2.  Helms M, S. Ethelberg, K. Mølbak and the DT104 study group. A Global Survey of Multidrug-resistant Salmonella Typhimurium, with Particular Reference to DT104, 1992-2001. Emerg Infect Dis 2005;11:859-67.
3. von Gottberg A, de Gouveia L, Madhi SA, du Plessis M, Quan V, Soma K, Huebner R, Flannery B, Schuchat A, Klugman KP, and the Group for Enteric, Respiratory and Meningeal disease Sur­veillance in South Africa (GERMS-SA). Impact of conjugate Haemophilus influenzae type b vaccine introduction in South Africa. Bulletin of WHO 2006;84:811-818.
4.  Wadula J, von Gottberg A, Kilner D, de Jong G, Cohen C, Khoosal M, Keddy K, Crewe-Brown H. Nosocomial outbreak of extended-spectrum β-lactamase-producing Salmonella Isangi in paediatric wards. Paed Infect Dis J 2006;25:843-844
5. McCarthy KM, Morgan J, Wannemuehler KA, Mirza SA, Gould SM, Mhlongo N, Moeng P, Maloba BR, Crewe-Brown HH, Brandt ME and Hajjeh RA for the Gauteng Cryptococcal Surveillance Initiative Group. Population-based surveillance for cryptococcosis in an antiretroviral-naïve South African province with high HIV seroprevalence. AIDS 2006; 20:2199-2206.
6. Morgan J, McCarthy KM, Gould S, Fan K, Arthington-Skaggs B, Iqbal N, Stamey K, Hajjeh RA and Brandt ME for the Gauteng Cryptococcal Surveillance Initiative Group. Cryptococcus gattii infection: characteristics and epidemiology of cases identified in a South African province with high HIV seroprevalence, 2002-2004. Clin Infect Dis 2006; 43:1077-80.
7.   Coulson G, von Gottberg A, du Plessis M, Smith AM, de Gouveia L, Klugman KP, for the Group for Enteric, Respiratory and Meningeal disease Surveillance in South Africa (GERMS-SA). Meningo­coccal disease in South Africa, 1999-2002. Emerg Infect Dis 2007;13(2):273-281.
8. Keddy KH, Nadan S, Govend C, Sturm AW for GERMS-SA. Evidence for a clonally different origin of the two cholera epidemics of 2001-2002 and 1980-1987 in South Africa. J Med Microbiol 2007;56(12):1644-50.
9. Smith AM, Gouws A-M., Hoyland G, Sooka A, Keddy KH, for the Group for Enteric, Respiratory and Meningeal disease Surveillance in South Africa (GERMS-SA). Outbreaks of food-borne disease: A common occurrence but rarely reported. S Afr Med J 2007;97(12):1272.
10.  R Wollin on the behalf of the Enternet participants. A study of invasiveness of different Salmonella serovars based on analysis of the Enternet database. Euro Surveill 2007;12(9):E070927.3 Erratum in: Euro Surveill 2007;12(10):E071004.6
11. Govender N. HIV-associated opportunistic fungal infections: a guide to using the clinical microbiology laboratory. S Afr J HIV Med 2007;Spring edition:18-23.
12.  McCarthy KM, Meintjes G, Arthington-Skaggs B, Bicanic T, Cotton M, Chiller T, Govender N, Harrison T, Karstaedt AS, Maartens G, Rabie H, Varavia E, Venter WDF, Vismer H. Guidelines for the Prevention, Diagnosis and Management of Cryptococcal Meningitis and Disseminated Crypto­coccosis in HIV-infected patients. S Afr J HIV Med 2007;Spring edition:25-35.
13.  von Gottberg A, du Plessis M, Cohen C, Prentice E, Schrag S, de Gouveia L, Coulson G, de Jong G, Klugman K. Emergence of endemic serogroup W135 meningococcal disease associated with a high mortality rate in South Africa. Clin Infect Dis 2008;46:377-86.
14. Wolter N, du Plessis M, von Gottberg A, de Gouveia L, Klugman KP. Molecular characterizatio­n of emerging levofloxacin-nonsusceptible pneumococci in children in South Afric­a. J Clin Microbiol 2009;47:1319-24
15. Smith AM, De Wee L, Keddy KH. Characterization of cholera outbreak isolates from Namibia, December 2006 to February 2007. Epidemiology and Infection 2008;136:1207-1209.
16.  McCarthy KM, Cohen C, Schneider H, Gould SM, Brandt ME and Hajjeh RA for the Gauteng Cryptococcal Surveillance Initiative Group. The burden of disease due to AIDS in Gauteng: inferred evidence from results of surveillance for cryptococcosis 2002-4. S Afr Med J 2008;98 (6):452-454.
17. Whitney AM, Coulson GB, von Gottberg A, Block C, Keller N, Mayer LW, Messonnier NE, Klugman KP. Genotypic comparison of invasive Neisseria meningitidis serogroup Y isolates from the United States, South Africa, and Israel, isolated from 1999 through 2002. J Clin Microbio­l 2009;47:2787-93
18.   Murphy E, Andrew L, Lee KL, Dilts DA, Nunez L, Fink PS, Ambrose K, Borrow R, Findlow J, Taha MK, Deghmane AE, Kriz P, Musilek M, Kalmusova J, Caugant DA, Alvestad T, Mayer LW, Sacchi CT, Wang X, Martin D, von Gottberg A, du Plessis M, Klugman KP, Anderson AS, Jansen KU, Zlotnick GW, Hoiseth SK. Sequence Diversity of the Factor H Binding Protein Vaccin­e Candidate in Epidemiologically Relevant Strains of Serogroup B Neisseria men­ingitidisJ Infect Dis 2009;200:379-89.
19. Smith AM, Keddy KH, Sooka A, Ismail H, Dejong GM; Group for Enteric, Respiratory and Meningea­l disease Surveillance in South Africa (GERMS-SA). Analysis of a temporal cluster of Shigella boydii isolates in Mpumalanga, South Africa, November to December 2007. J Infect Dev Ctries. 2009;3(1):65-70.
20.  Smith AM, Sooka A, Ismail H, Nadan S, Crisp N, Weenink E, Keddy KH; Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa (GERMS-SA). Analysis of Vibri­o cholerae isolates from the Northern Cape province of South Africa. J Med Microbiol. 2009;58(1):151-4.
21.    Keddy, K.H., Dwarika, S., Crowther, P., Perovic, O., Wadula, J., Hoosen, A., Sooka, A., Crewe-Brown, H.H., Smith, A.M.  Genotypic and Demographic Characterisation of Invasive Isolates of Salmonella Typhimurium Mainly in Patients Co-infected With HIV in Gauteng, South Africa, 2006-2007. Journal of Infection in Developing Countries 2009; 3(8), 585-592.
22. Govender N, Smith AM, Karstaedt AS, Keddy KH; Group for Enteric, Respiratory and Meningeal­ disease Surveillance in South Africa (GERMS-SA). Plasmid-mediated quinolone resistanc­e in Salmonella from South Africa. J Med Microbiol. 2009;58(10):1393-4.
23. Park BJ, Wannemuehler KA, Marston BJ, Govender N, Pappas PG, Chiller TM. Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS. AIDS 2009:23;525-30.
24.   Feldman C, Brink AJ, von Gottberg A, Wolter N, de Gouveia L, Perovic O, Klugman KP. Antimicrobial susceptibility of pneumococcal isolates causing bacteraemic pneumococcal pneumonia: analysis using current breakpoints and fluoroquinolone pharmacodynamics. Int J Antimicrob Agents 2010;36:95-97.
25.  Mothibeli KM, du Plessis M, von Gottberg A, de Gouveia L, Adrian P, Madhi SA, Klugman KP. An unusual pneumococcal sequence type is the predominant cause of serotype 3 invasive disease in South Africa. J Clin Microbiol 2010;48:184-91
26.  Cohen C, Singh E, Wu HM, Martin S, de Gouveia L, Klugman KP, Meiring S, Govender N, von Gottberg A. Increased incidence of meningococcal disease in HIV-infected individuals associated with higher case-fatality ratios in South Africa. AIDS 2010;24:1351-60.
27.  du Plessis M, de Gouveia L, Skosana H, Thomas J, Blumberg L, Klugman KP, von Gottberg A. Invasive Neisseria meningitidis with decreased susceptibility to fluoroquinolones in South Africa, 2009. J Antimicrob Chemother 2010;65:2258-60.
28.   Fali A, du Plessis M, Wolter N, Klugman KP, von Gottberg A. Single report of beta-lactam resistance in an invasive Haemophilus influenzae isolate from South Africa mediated by mutations in penicillin-binding protein 3, 2003-2008. Int J Antimicrob Agents 2010;36:480-482.
29.  Smith AM, Govender N, Keddy KH, for the Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa (GERMS-SA). Quinolone-resistant Salmonella Typhi in South Africa, 2003-2007. Epidemiology and Infection 2010;138:86-90.
30.   Keddy KH, Smith AM, Sooka A, Ismail H, Oliver S. Fluoroquinolone-resistant typhoid, South Africa. Emerging Infectious Diseases 2010;16:879-880.
31.    Feasey N, Archer BN, Heyderman RS, Gordon MA, Keddy KH. Typhoid Fever and invasive Non-Typhoid Salmonellosis, Malawi and South Africa. Emerging Infectious Diseases 2010; 16:1448-1451.
32.  Croucher NJ, Harris SR, Fraser C, Quail MA, Burton J, van der Linden M, McGee L, von Gottberg A, Song JH, Ko KS, Pichon B, Baker S, Parry CM, Lambertsen LM, Shahinas D, Pillai DR, Mitchell TJ, Dougan G, Tomasz A, Klugman KP, Parkhill J, Hanage WP, Bentley SD. Rapid pneumococcal evolution in response to clinical interventions. Science 2011;331:430-434.
33.  Nunes MC, von Gottberg A, de Gouveia L, Cohen C, Moore DP, Klugman KP, Madhi SA. The impact of antiretroviral treatment on the burden of invasive pneumococcal disease in South African children: a time series analysis. AIDS 2011;25:453-62.
34.   Nyasulu P, Cohen C, de Gouveia L, Feldman C, Klugman KP, von Gottberg A. Increased Risk of Death in Human Immunodeficiency Virus-infected Children With Pneumococcal Meningitis in South Africa, 2003-2005. Pediatr Infect Dis J 2011;30:1075-80.
35.   Son MR, Shchepetov M, Adrian PV, Madhi SA, de Gouveia L, von Gottberg A, Klugman KP, Weiser JN, Dawid S. Conserved Mutations in the Pneumococcal Bacteriocin Transporter Gene, blpA, Result in a Complex Population Consisting of Producers and Cheaters. MBio 2011;2:e00179-11.
36.  Silberbauer EJ, Ismail N, von Gottberg A, Hoosen AA. Serotype and antimicrobial profile distribution of invasive pneumococcal isolates in the pre-vaccine introduction era in Pretoria, South Africa, 2005 through 2009. Diagn Microbiol Infect Dis 2011;71:309-11.
37.  Nunes MC, von Gottberg A, de Gouveia L, Cohen C, Kuwanda L, Karstaedt AS, Klugman KP, Madhi SA. Persistent High Burden of Invasive Pneumococcal Disease in South African HIV-Infected Adults in the Era of an Antiretroviral Treatment Program. PLoS One 2011;6:e27929
38.    Moodley T, Lekalakala M R, de Gouveia L, Dangor Y, Hoosen A A. Meningococcal infections in hospitalised patients in Pretoria.S Afr Med J 2011;101:736-738.
39. Mothibeli KM, du Plessis M, von Gottberg A, Murphy E, Hoiseth SK, Zlotnick G, Klugman KP. Distribution of factor H binding protein beyond serogroup B: variation among five serogroups of invasive Neisseria meningitidis in South Africa. Vaccine 2011;29:2187-92.
40.  Keddy KH, Sooka A, Ismail H, Smith AM, Weber I, Letsoalo ME, Harris BN for GERMS SA. Molecular epidemiological investigation of a typhoid fever outbreak in Delmas, South Africa 2005: the relationship to a prior epidemic in 1993. Epidemiol Infect 2011;139: 1239-45
41.  Smith AM, Tau NP, Sooka A, Keddy KH for the Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa (GERMS-SA). Surveillance for enterohaemorrhagic Escherichia coli associated with human diarrhoea in South Africa, 2006-2009. J Med Microbiol 2011;60:681-683.
42.    Ismail H, Smith AM, Sooka A, Keddy KH for the Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa (GERMS-SA). Genetic characterisation of multi-drug resistant, β-lactamase producing Vibrio cholerae O1 outbreak strains, Mpumalanga, South Africa, 2008. J Clin Microbiol 2011; 49: 2976-79.
43. Crowther-Gibson P, Govender N Lewis DA, Bamford C, Brink A (principal authors). Von Gottberg A, Klugman K, Du Plessis M, Fali A, Harris B, Keddy K, Botha M (co-authors). Part IV. Human infections and antibiotic resistance. South Afr Med J Suppl.: The Global Antibiotic Resistance Partnership. 2011;101:567-578.
44.  Bamford C, Brink A, Govender N, Lewis DA (principal authors). Botha M, Harris B, Keddy K, Gelband H, Duse AG (co-authors). Part V. Surveillance activities. South Afr Med J Suppl.: The Global Antibiotic Resistance Partnership. 2011; 01:579-582.
45.  Park BJ, Shetty S, Ahlquist A, Greenbaum A, Miller JL, Motsi A, McCarthy K, Govender N; for the Gauteng Cryptococcal Surveillance Initiative Group. Long-term follow-up and survival of antiretroviral-naive patients with cryptococcal meningitis in the pre-antiretroviral therapy era, Gauteng Province, South Africa. Int J STD AIDS. 2011 Apr;22(4):199-20
46.  Govender NP, Patel J, van Wyk M, Chiller TM, Lockhart SR; for the Group for Enteric, Respiratory and Meningeal disease Surveillance in South Africa (GERMS-SA). Trends in Antifungal Drug Susceptibility of Cryptococcus neoformans Obtained Through Population-based Surveillance, South Africa, 2002-2003 and 2007-2008. Antimicrob Agents Chemother. 2011 Jun;55(6):2606-11.
47.    Miglia KJ, Govender NP, Rossouw J, Meiring S, Mitchell TG; Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa. Analyses of pediatric isolates of Cryptococcus neoformans from South Africa. J Clin Microbiol. 2011 Jan;49(1):307-14.
48. Madhi SA, Cohen C, von Gottberg A. Introduction of pneumococcal conjugate vaccine into the public immunization program in South Africa: translating research into policy. Vaccine 2012; 30 Suppl 3:C21-C27.
49. Wyres KL, Lambertsen LM, Croucher NJ, McGee L, von Gottberg A, Linares J, Jacobs MR, Kristinsson KG, Beall BW, Klugman KP, Parkhill J, Hakenbeck R, Bentley SD, Brueggemann AB. The multidrug-resistant PMEN1 pneumococcus is a paradigm for genetic success. Genome Biol 2012; 13:R103.
50.    Soeters HM, von Gottberg A, Cohen C, Quan V, and Klugman KP. Trimethoprim-Sulfamethoxazole Prophylaxis and Antibiotic Nonsusceptibility in Invasive Pneumococcal Disease. Antimicrob Agents Chemother 2012;56:1602-1605
51.  Moodley C, du Plessis M, Ndlangisa K, de Gouveia L, Klugman KP, von Gottberg A. Clonal Analysis of Neisseria meningitidis Serogroup B Strains in South Africa, 2002 to 2006: Emergence of New Clone ST-4240/6688. J Clin Microbiol 2012; 50:3678-86.
52. Tau NP, Smith AM, Sooka A, Keddy KH for GERMS-SA. Molecular characterization of extended-spectrum beta-lactamase-producing Shigella isolates from humans in South Africa, 2003-2009.  J Med Microbiol 2012;61:162-164.
53.    Tau NP, Meidany P, Smith AM, Sooka A, Keddy KH for the Group for Enteric, Respiratory, and Meningeal Disease Surveillance in South Africa. Escherichia coli O104 associated with human diarrhea, South Africa, 2004-2011. Emerg Infect Dis. 2012; 18(8):1314-1317.
54.    Keddy KH, Sooka A, Crowther-Gibson P, Quan V, Meiring S, Cohen C, Nana T, Sriruttan C, Seetharam S, Hoosen A, Naicker P, Elliott E, Haffejee S, Whitelaw A, Klugman KP, for the Group for Enteric, Respiratory, and Meningeal Disease Surveillance in South Africa (GERMS-SA). Systemic Shigellosis in South Africa. Clin Infect Dis. 2012;54(10): 1448-1454.
55.  Espinel-Ingroff A, Chowdhary A, Cuenca-Estrella M, Fothergill A, Fuller J, Hagen F, Govender N, Guarro J, Johnson E, Lass-Flörl C, Lockhart SR, Martins MA, Meis JF, Melhem MS, Ostrosky-Zeichner L, Pelaez T, Pfaller MA, Schell WA, Trilles L, Kidd S, Turnidge J. Cryptococcus neoformans-Cryptococcus gattii Species Complex: An International Study of Wild-Type Susceptibility Endpoint Distributions and Epidemiological Cutoff Values for Amphotericin B and Flucytosine. Antimicrob Agents Chemother. 2012 Jun; 56(6):3107-13. 
56. Jarvis JN, Govender N, Chiller T, Park BJ, Longley N, Meintjes G, Bekker LG, Wood R, Lawn SD, Harrison TS. Cryptococcal Antigen Screening and Pre-emptive Therapy in Patients Initiating Antiretroviral Therapy in Resource-Limited Settings: A Proposed Algorithm for Clinical Implementation. J Int Assoc Physicians AIDS Care 2012. 2012 Nov-Dec;11(6):374-9.
57.    Govender NP, Roy M, Oladoyinbo S, Maotoe T, Stevens W, Pinini Z, Spencer D, Venter WDF, Jassat W, Cameron D, Meintjes G, Chiller T, Chetty V, Mbengashe T and Pillay Y for the South African Cryptococcal Screening Initiative Group. Phased Implementation of Screening for Cryptococcal Disease in South Africa. S Afr Med J. 2012 Oct 8;102(12):914-7.
58. Meiring ST, Quan VC, Cohen C, Dawood H, Karstaedt AS, McCarthy KM, Whitelaw AC, Govender NP for the Group for Enteric, Respiratory and Meningeal disease Surveillance in South Africa (GERMS-SA). A comparison of paediatric- and adult-onset cryptococcosis detected through population-based surveillance in South Africa, 2005-2007.  AIDS. 2012 Nov 28;26(18):2307-14. doi: 10.1097/QAD.0b013e3283570567.
59.    Klausner J, Govender N, Oladoyinbo S, Roy M, Chiller T. Response to Parkes-Ratanshi R, Wakeham K, Levin J, et al. Primary prophylaxis of cryptococcal disease with fluconazole in HIV-positive Ugandan adults: a double-blind, randomized, placebo-controlled trial. Lancet Infect Dis. 2012 Jun; 12(6):431-2.
60.   Wyres KL, Lambertsen LM, Croucher NJ, McGee L, von Gottberg A, Linares J, Jacobs MR, Kristinsson KG, Beall BW, Klugman KP, Parkhill J, Hakenbeck R, Bentley SD, Brueggemann AB. Pneumococcal capsular switching: a historical perspective. J Infect Dis 2013; 207:439-49.
61.   von Gottberg A, Cohen C, de Gouveia L, Meiring S, Quan V, Whitelaw A, Crowther-Gibson P, Madhi SA, Whitney CG, Klugman KP. Epidemiology of invasive pneumococcal disease in the pre-conjugate vaccine era: South Africa, 2003-2008. Vaccine 2013; 31:4200-4208.
62.    Ismail H, Smith AM, Tau NP, Sooka A, Keddy KH for the Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa (GERMS-SA). Cholera outbreak in South Africa, 2008-2009: Laboratory analysis of Vibrio cholerae O1 strains. J Infect Dis. 2013;208: S39-S45.
63.    Govender NP, Meintjes G, Bicanic T, Dawood H, Harrison TS, Jarvis JN, Karstaedt AS, Maartens G, McCarthy KM, Rabie H, Variava E and Venter WDF. Guideline for Prevention, Diagnosis and Management of Cryptococcal Meningitis among HIV-infected Persons: 2013 Update. S Afr J HIV Med 2013; 14(2):76-86.
64.    du Plessis M, Wolter N, Crowther-Gibson P, Hamstra HJ, Schipper K, Moodley C, Cohen C, van de Beek D, van der Ley P, von Gottberg A, van der Ende A. Meningococcal serogroup Y lpxL1 variants from South Africa are associated with clonal complex 23 among young adults. J Infect 2014; 68:455-61.
65.  von Gottberg A, de Gouveia L, Tempia S, Quan V, Meiring S, von Mollendorf C, Madhi SA, Zell ER, Verani JR, O'Brien KL, Whitney CG, Klugman KP, Cohen C. Effects of vaccination on invasive pneumococcal disease in South Africa. N Engl J Med 2014;371:1889-99.
66. Ndlangisa KM, du Plessis M, Wolter N, de Gouveia L, Klugman KP, von Gottberg A. Population Snapshot of Streptococcus pneumoniae Causing Invasive Disease in South Africa Prior to Introduction of Pneumococcal Conjugate Vaccines. PLoS One 2014;9:e107666.
67.    van Tonder AJ, Mistry S, Bray JE, Hill DM, Cody AJ, Farmer CL, Klugman KP, von Gottberg A, Bentley SD, Parkhill J, Jolley KA, Maiden MC, Brueggemann AB. Defining the estimated core genome of bacterial populations using a Bayesian decision model. PLoS Comput Biol 2014;10:e1003788.
68.    Magomani V, Wolter N, Tempia S, du Plessis M, de Gouveia L, von Gottberg A. Challenges of using molecular serotyping for surveillance of pneumococcal disease. J Clin Microbiol 2014;52:3271-76.
69.   von Mollendorf C, Cohen C, de Gouveia L, Quan V, Meiring S, Feldman C, Klugman KP, von Gottberg A. Factors Associated with Ceftriaxone Nonsusceptibility of Streptococcus pneumoniae: Analysis of South African National Surveillance Data, 2003 to 2010. Antimicrob Agents Chemother 2014;58:3293-305.
70.   Dangor Z, Izu A, Moore DP, Nunes MC, Solomon F, Beylis N, von Gottberg A, McAnerney JM, Madhi SA. Temporal association in hospitalizations for tuberculosis, invasive pneumococcal disease and influenza virus illness in South African children. PLoS One 2014;9:e91464.
71.  von Mollendorf C, Cohen C, de Gouveia L, Naidoo N, Meiring S, Quan V, Lindani S, Moore DP, Reubenson G, Moshe M, Eley B, Hallbauer UM, Finlayson H, Madhi SA, Conklin L, Zell ER, Klugman KP, Whitney CG, von Gottberg A; for the South African IPD Case-Control Study Group. Risk Factors for Invasive Pneumococcal Disease among Children less Than 5 Years of Age in a High HIV-Prevalence Setting, South Africa, 2010 to 2012. Pediatr Infect Dis J. 2015 Jan; 34 (1): 27–34 Epub 2014 Jul 3
72.  van Wyk M, Govender NP, Mitchell TG, Litvintseva AP; GERMS-SA. Multilocus Sequence Typing of Serially Collected Isolates of Cryptococcus from HIV-Infected Patients in South Africa. J Clin Microbiol. 2014 Mar 19.
73.  Govender NP and Dlamini S. Management of HIV-associated cryptococcal disease in South Africa. S Afr Med J. 2014;104 (12): 896.
74.    Govender NP, Meintjes G and Banoo S. Access to flucytosine for HIV-infected patients with cryptococcal meningitis: an urgent need. S Afr Med J 2014: In press.
75.    Magobo RE, Corcoran C, Seetharam S, Govender NP. Candida auris-Associated Candidemia, South Africa. Emerg Infect Dis. 2014 Jul;20(7).
76.    Jarvis JN, Bicanic T, Loyse A, Meintjes G, Hogan L, Roberts CH, Shoham S, Perfect JR, Govender NP, Harrison TS. Very Low Levels of 25-Hydroxyvitamin D Are Not Associated With Immunologic Changes or Clinical Outcome in South African Patients With HIV-Associated Cryptococcal Meningitis. Clin Infect Dis. 2014 Aug 15;59(4):493-500.
77.    Loyse A, Thangaraj H, Govender NP, Harrison T, Bicanic T; all authors. Access to antifungal medicines in resource-poor countries - authors' reply. Lancet Infect Dis. 2014 May;14(5):371.
78.    Govender NP, Roy M, Mendes JF, Zulu TG, Chiller TM and Karstaedt AS. Evaluation of Screening and Treatment of Cryptococcal Antigenaemia among HIV-infected Persons in Soweto, South Africa. HIV Med 2015. HIV Med. 2015 Sep;16(8):468-76. doi: 10.1111/hiv.12245. Epub 2015 Feb 17.
79.    Longley N, Jarvis JN, Meintjes G, Boulle A, Cross A, Kelly N, Govender NP, Bekker LG, Wood R, Harrison TS. Cryptococcal Antigen Screening in Patients Initiating ART In South Africa: A Prospective Cohort Study. Clin Infect Dis. 2015 Nov 12. pii: civ936. Clin Infect Dis. 2016 Mar 1;62(5):581-7.
80.    Espinel-Ingroff A, Alvarez-Fernandez M, Cantón E, Carver PL, S. C-A. Chen, G. Eschenauer, D. L. Getsinger, G. M. Gonzalez, Govender NP, A. Grancini, K. E. Hanson, S. E. Kidd, K. Klinker, C. J. Kubin, J.V. Kus, S. R. Lockhart, J. Meletiadis, A. J. Morris, T. Pelaez, G. Quindós, M. Rodriguez-Iglesias, F. Sánchez-Reus, S. Shoham, N. L. Wengenack, N. Borrell Solé, J. Echeverria, J. Esperalba, E. Gómez-G. de la Pedrosa, I. García García, M. J. Linares, F. Marco, P. Merino, J. Pemán, L. Pérez del Molino, E. Roselló Mayans, C. Rubio Calvo, M. Ruiz Pérez de Pipaon, G. Yagüe, G. Garcia-Effron, J. Guinea, D. S. Perlin, M. Sanguinetti, R. Shields, and J. Turnidge. A multi-center study of epidemiological cutoff values and detection of resistance in Candida spp. to anidulafungin, caspofungin and micafungin using the Sensititre YeastOne colorimetric method. Antimicrob. Agents Chemother. 2015 Nov;59(11):6725-32. doi: 10.1128/AAC.01250-15. Epub 2015 Aug 17.
81.    von Mollendorf C, von Gottberg A, Tempia S, Meiring S, de Gouveia L, Quan V, Lengana S, Aveneant T, du Plessis N , Eley B, Finlayson H, Reubenson G, Moshe M, O’Brien KL, Klugman KP, Whitney CG, Cohen C, for the Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa (GERMS-SA). Increased risk and mortality of invasive pneumococcal disease in HIV-exposed-uninfected infants <1 year of age in South Africa, 2009-2013. Clin Infect Dis. 2015 May 1;60(9):1346-56. doi: 10.1093/cid/civ059. Epub 2015 Feb 2.
82.    Cohen C, Naidoo N, Meiring S, de Gouveia L, von Mollendorf C, Walaza S, Naicker P, Madhi SA, Feldman C, Klugman KP, Dawood H, von GottbergA for GERMS-SA. Streptococcus pneumoniae serotypes and mortality in adults and adolescents in South Africa: analysis of national surveillance data, 2003 – 2008. PLoS One. 2015 Oct 13;10(10):e0140185. doi: 10.1371/journal.pone.0140185. eCollection 2015
83.    von Mollendorf C, Cohen C, de Gouveia L, Naidoo N, Meiring S, Quan V, Lindani S, Moore DP, Reubenson G, Moshe M, Eley B, Hallbauer UM, Finlayson H, Madhi SA, Conklin L, Zell ER, Klugman KP, Whitney CG, von Gottberg A; South African IPD Case–Control Study Group. Risk factors for invasive pneumococcal disease among children less than 5 years of age in a high HIV prevalence setting, South Africa, 2010 to 2012. Pediatr Infect Dis J. 2015 Jan;34(1):27-34. doi: 10.1097/INF.0000000000000484.
84.    von Mollendorf C, Cohen C, Tempia S, Meiring S, de Gouveia L, Quan V, Lengana S, Karstaedt A, Dawood H, Seetharam S, Lekalakala R, Madhi SA, Klugman KP, von Gottberg A for GERMS-SA. Epidemiology of Serotype 1 Invasive Pneumococcal Disease, South Africa, 2003–2013. Emerg Infect Dis.2016; 22(2):261-270. DOI: 10.3201/eid2202.150967.
85.    Smith AM, Tau N, Sooka A, Keddy KH for GERMS-SA. Microbiological characterization of Salmonella enterica serotype Paratyphi, South Africa, 2003-2014. J Med Microbiol. 2015 Aug 24. doi: 10.1099/jmm.0.000161.
86.    Keddy KH, Sooka A, Musekiwa A, Smith AM, Ismail H, Tau NP, Crowther-Gibson P, Angulo FJ, Klugman KP; Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa (GERMS-SA); Group for Enteric Respiratory and Meningeal Disease Surveillance in South Africa GERMS-SA. Clinical and microbiological features of Salmonella Meningitis in a South African Population, 2003-2013. Clin Infect Dis. 2015 Nov 1;61 Suppl 4:S272-82. doi: 10.1093/cid/civ685. (Nominated for Shepard Award)
87.    Singh-Moodley A, Ekermans P and Perovic O. Emerging Carbapenem-Resistant Enterobacter cloacae Producing OXA-48-, VIM- and IMP-Type-β-lactamases in Eastern Cape Hospitals in South Africa. Open Journal of Medical Microbiology 2015; 5, 246-253. DOI: 10.4236/ojmm.2015.54030.
88.    Singh-Moodley A, Marais E and Perovic O. Discrepancies between Genotypic and Phenotypic identification of Methicillin-Resistant Staphylococcus aureus and absence of mecC in surveillance isolates in South Africa. Southern African Journal of Infectious Diseases 2015; 1(1):1-3. http://dx.doi.org/10.1080/23120053.2015.1107256
89.Perovic O, Iyaloo S, Kularatne R, Lowman W, Bosman N, Wadula J, et al. (2015) Prevalence and Trends of Staphylococcus aureus Bacteraemia in Hospitalized Patients in South Africa, 2010 to 2012:Laboratory-Based Surveillance Mapping of Antimicrobial Resistance and Molecular Epidemiology. PLoS ONE. 2015;10(12): e0145429. doi:10.1371/journal.pone.0145429  
90.    Govender NP, Patel J, Magobo RE, Naicker S, Wadula J, Whitelaw A, Coovadia Y, Kularatne R, Govind C, Lockhart SR, Zietsman IZ on behalf of the TRAC-South Africa group. Emergence of Azole-Resistant Candida parapsilosis causing Bloodstream Infection: Results from Laboratory-Based Sentinel Surveillance, South Africa. J Antimicrob Chemother. 2016 Jul;71(7):1994-2004. Epub 2016 Apr 28.
91.    Wake R, Sriruttan C, Glencross DK, Harrison TS, Govender NP. Cryptococcal Antigen Screening in HIV-infected Adults - let's get straight to the point-of-care. AIDS. 2016 Jan 28;30(3):339-42.
92.    Naicker S, Magobo RE, Zulu TG, Maphanga TG, Luthuli N, Lowman W and Govender NP. Two echinocandin-resistant Candida glabrata FKS mutants from South Africa. Med Mycol Case Rep 2016. Mar 21;11:24-6. doi: 10.1016/j.mmcr.2016.03.004. eCollection 2016 Mar.
93.    Naicker S, Govender N, Patel J, Zietman IL, Wadula J, Coovadia Y, Kularatne R, Seetharam S and Govender NP. Comparison of species-level identification and antifungal susceptibility results from diagnostic and reference laboratories for bloodstream Candida surveillance isolates, South Africa, 2009-2010. Med Mycol 2016  Jun22.pii:myw046[Epub ahead of print]
94.    Vallabhaneni S, Longley N, Smith M, Smith R, Osler M, Kelly N, Cross A, Boulle A, Meintjes G, Govender NP. Evaluation of a Public-sector, Provider-initiated Cryptococcal Antigen Screening and Treatment Program, Western Cape, South Africa. J Acquir Immune Defic Syndr. 2016 Jun 1;72(2):e37-42. doi: 10.1097/QAI.0000000000000976.
95.    Wake R and Govender NP. Cryptococcosis in apparently immune-competent patients: taxonomy, epidemiology, pathophysiology and treatment. S Afr J Infect Dis 2016; 31(2):32-34.
96.    du Plessis D, Poonsamy B, Msimang V, Davidsson L, Cohen C, Govender NP, Dawood H, Karstaedt AS, Frean J (2016): Laboratory-based surveillance of Pneumocystis jirovecii pneumonia in South Africa, 2006–2010, Southern African Journal of Infectious Diseases, DOI:10.1080/23120053.2015.1118828
97.    Meiring S, Cohen C, Quan V, de Gouveia L, Feldman C, Karstaedt A, Klugman KP, Madhi SA, Rabie H, Sriruttan C, von Gottberg A, for GERMS-SA. HIV infection and the epidemiology of invasive pneumococcal disease (IPD) in South African adults and older children prior to the introduction of a pneumococcal conjugate vaccine (PCV). PLoS One. 2016;11(2):e0149104.
98.    von Mollendorf C, Cohen C, Tempia S, Meiring S, de Gouveia L, Quan V, Lengana S, Karstaedt A, Dawood H, Seetharam S, Lekalakala R, Madhi SA, Klugman KP, von Gottberg A, for GERMS-SA. Epidemiology of serotype 1 invasive pneumococcal disease, South Africa, 2003-2013. Emerg Infect Dis. 2016;22(2):261-270.
99.    du Plessis M, Allam M, Tempia S, Wolter N, de Gouveia L, von Mollendorf C, Jolley KA, Mbelle N, Wadula J, Cornick JE, Everett DB, McGee L, Breiman RF, Gladstone RA, Bentley SD, Klugman KP, von Gottberg A. Phylogenetic Analysis of Invasive Serotype 1 Pneumococcus in South Africa, 1989 to 2013. J Clin Microbiol. 2016 May;54(5):1326-34. doi: 10.1128/JCM.00055-16. Epub 2016 Mar 9
101. Meiring S, Fortuin-de Smidt M, Kularatne R, Dawood H, Govender NP; GERMS-SA. Prevalence and Hospital Management of Amphotericin B Deoxycholate-Related Toxicities during Treatment of HIV-Associated Cryptococcal Meningitis in South Africa. PLoS Negl Trop Dis. 2016 Jul 28;10(7):e0004865. doi: 10.1371/journal.pntd.0004865. eCollection 2016 Jul.
 
Non-peer reviewed publications

1.   Coulson GB, von Gottberg A, Smith A, Klugman K and the National Surveillance Network.  Meningo­coccal Outbreak 2003: Investigation of a community-based outbreak of serogroup C Neisseria meningitidis in South Africa. Communicable Diseases Surveillance Bulletin 2003;1(1)13-16.
2.  Keddy K. Typhoid Fever. Communicable Diseases Surveillance Bulletin September 2004;2(4):6-8. Available from: http://www.nicd.ac.za/assets/files/CommDisBullSept04.pdf
3. Keddy K. Cholera. Communicable Diseases Surveillance Bulletin November 2004;2(5):5  Available from http://www.nicd.ac.za/assets/files/CommDisBullNov04.pdf
4. Keddy K. Enteric Disease Surveillance, 2004. Communicable Diseases Surveillance Bulletin January 2005;3(1):6-7. Available from: http://www.nicd.ac.za/assets/files/CommDisBullJan052.pdf
5.      Prentice E, de Gouveia L, Quan V, von Gottberg A and GERMS-SA. Respiratory and Meningeal Pathogens surveillance, 2004. Communicable Diseases Surveillance Bulletin January 2005;3(1):7-8. Available from: http://www.nicd.ac.za/assets/files/CommDisBullJan052.pdf
6.  Nadan S, Keddy K. Quinolone Resistance in Enteric Bacteria. Communicable Diseases Surveillance Bulletin August 2005;3(3):5-7. Available from: http://www.nicd.ac.za/pubs/survbull/2005/CommDisBullAugust05.pdf
7.      Keddy K. South African Laboratory Surveillance for Enteric Diseases, 2005. Communicable Diseases Surveillance Bulletin March 2006;4(1):3. Available from: http://www.nicd.ac.za/assets/files/CommDisBullMarch06.pdf
8.     von Gottberg A, de Gouveia L. Respiratory and Meningeal Pathogens Surveillance, South Africa, 2005. Communicable Diseases Surveillance Bulletin March 2006;4(1):4-8. Available from: http://www.nicd.ac.za/assets/files/CommDisBullMarch06.pdf
9. GERMS-SA Surveillance Report 2006: von Gottberg A, de Gouveia L. Respiratory and Meningeal Pathogens Surveillance, South Africa, 2006. McCarthy K. Cryptococcal surveillance, South Africa, 2006. Frean J. Pneumocystis jirovecii pneumonia (PCP) Surveillance, South Africa, 2006. Keddy K. Enteric diseases surveillance, South Africa, 2006. Communicable Diseases Surveillance Bulletin March 2007; 5(1):10-19. Available from http://www.nicd.ac.za/assets/files/CommDisBullMarch07.pdf
10.  von Gottberg A. Prevention of Pneumococcal Disease in Children: the Age of the Polysaccharide-Protein Conjugate Pneumococcal Vaccine. Communicable Diseases Surveillance Bulletin 2007 May;5(2):5-6. Available from: http://www.nicd.ac.za/assets/files/CommDisBullMay07.pdf
11.  GERMS-SA Surveillance Report for South Africa, 2007. Communicable Diseases Surveillance Bulletin 2008 March; 6(1):12-27. Available from http://www.nicd.ac.za/assets/files/CommDisBullMarch08_Vol0601.pdf
12.      Crowther P, Cohen C, Govender N, Keddy K and von Gottberg A. Predictors of non-reporting to a national laboratory-based surveillance programme. Communicable Diseases Surveillance Bulletin 2008 November; 6(4):1-4 http://www.nicd.ac.za/assets/files/CommDisBullNov08_Vol0604.pdf
13.  GERMS-SA Surveillance Report for South Africa, 2008. Communicable Diseases Surveillance Bulletin 2009 March; 7(1):14-31. Available from http://www.nicd.ac.za/assets/files/CommDisBullMarch09_Vol0701.pdf
14.  GERMS-SA Surveillance Report for South Africa, 2009. Communicable Diseases Surveillance Bulletin 2010 May; 8(2):20-41. Available from http://www.nicd.ac.za/assets/files/CommDisBullMay10_Vol0802.pdf
15.   von Gottberg A. Bacterial meningitis in the era of paediatric vaccination against the encapsulated pathogens. CME (Continuing Medical Education) June 2010; 28 (6):198-202.]
16.  GERMS-SA Surveillance Report for South Africa, 2010. Communicable Diseases Surveillance Bulletin 2011 May; 9(2):32-56. Available from http://www.nicd.ac.za/assets/files/Bulletin%20May%202011.pdf
17.  GERMS-SA Surveillance Report for South Africa, 2011. Communicable Diseases Surveillance Bulletin 2012 August; 10(3):46-76. Available from http://www.nicd.ac.za/assets/files/Communicable%20Diseases%20Surveillance%20Bulletin%20August%202012.pdf
18.  GERMS-SA Surveillance Report for South Africa, 2012. Communicable Diseases Surveillance Bulletin 2013 September; 11(3):65-95. Available from http://www.nicd.ac.za/assets/files/NICD%20CommDisBull-%20August%202013(1).pdf
19. GERMS-SA Annual Report 2012. Available from http://www.nicd.ac.za/assets/files/GERMS-SA%202012%20Annual%20Report.pdf
20.  GERMS-SA Annual Report 2013. Available from http://www.nicd.ac.za/assets/files/GERMS-SA%20AR%202013.pdf
21.  GERMS-SA Annual Report 2014. Available from http://www.nicd.ac.za/assets/files/GERMS-SA%20AR%202013.pdf
22. Introduction to GERMS-SA clinic-based surveillance for TB, HIV and other STIs and related drug resistance. NICD Communicable Diseases Surveillance Bulletin 2015 June, 13(2): 62-64. Available from http://www.nicd.ac.za/assets/files/CommDisBull%2013(2)-June%202015.pdf