Malaria is a potentially life-threatening disease caused by blood parasites of the genus Plasmodium, which are transmitted via the bites of infected mosquitoes. In the human body, the parasites first multiply in the liver, and then infect the red blood cells. Malaria is preventable and curable. Increased malaria prevention and control measures are dramatically reducing the malaria burden. Globally, malaria is one of the six major causes of deaths from communicable diseases. 90% of world’s approximately 600 000 annual malaria deaths occur in Africa. In the last few years (2015-2018) South Africa has had between about 10 000 and 30 000 notified cases of malaria per year, and the National Department of Health is planning to eradicate it (i.e. no local transmission) by 2023. However, there are increasing problems with importation of malaria cases, vector control spraying programme delivery, vector insecticide resistance, and many health provision challenges that stand in the way of this objective.