The first-ever South African National TB Prevalence survey was a collaboration between the MRC, HSRC, NICD and NDoH. The survey aimed to establish the true burden of pulmonary TB disease in South Africa and was conducted according to the international recommendations of the WHO Global Task Force on TB Impact Measurement. The Centre for TB (NICD) was tasked with providing the laboratory services for the survey. Cases of presumptive TB were detected through an initial screening for TB symptoms and chest X-ray (CXR) of all eligible individuals, and a subsequent bacteriological examination of two sputum samples per individual. All sputum samples were processed for Xpert MTB/RIF Ultra and liquid TB culture. This was one of the first TB prevalence surveys to use the Xpert MTB/RIF Ultra for TB case detection. Findings from the survey were used to develop an algorithm for the management of patients with Xpert ‘Trace’ result. See section ‘’Advancing Diagnostics, Epidemiology and Treatment’’ for the algorithm.
TB Prevalence survey report (Feb 2021)
The CTB conducts and supports other countries to undertake population based survey and research to enhance our understanding of the disease burden and factors impacting on efforts aimed at controlling and eliminating TB and DR-TB. These are aimed at informing policy and practice.
South African Tuberculosis Drug Resistance Survey 2012–14