The South African National Cancer Registry (NCR), is a division of National Health Laboratory Services (NHLS). The NCR serves as South Africa’s main source of national cancer incidence data. Since 1986, the NCR has conducted pathology-based cancer surveillance, where data on cancer cases diagnosed by histology, cytology and bone marrow aspirate and trephine are collected, analysed and reported annually.

In 2011, Regulation no. 380 of the National Health Act no. 61 of 2003 was created to legally establish the NCR and to make cancer a reportable disease. The regulation provided a mandate to establish a population-based cancer registry. Since January 2017, population based cancer data are collected from Ekurhuleni metropolitan municipality in Gauteng Province. The Ekurhuleni Population Based Cancer Registry (EPBCR) meets the gold standard criteria for cancer registration worldwide as all cancers that are diagnosed clinically, radiologically and pathologically are collected. 


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