PEER REVIEWED PUBLICATIONS
HIV & STIs
2021
ADCC-mediating non-neutralizing antibodies can exert immune pressure in early HIV-1 infection
Mielke D, Bandawe G, Zheng J, Jones J, Abrahams M, Bekker V, Ochsenbauer C, Garrett N, Abdool Karim S, Moore PL, Morris L, Montefiori D, Anthony C, Ferrari G, Williamson C
An HIV vaccine protective allele in FCGR2C associates with increased odds of perinatal acquisition
Ebonwu J, Lassauniere R, Paximadis M, Goosen M, Strehlau R, Gray GE, Kuhn L, Tiemessen CT
An HIV Vaccine Protective Allele in FCGR2C associates with increased odds of Perinatal HIV
Ebonwu J, Lassaunière R, Paximadis M, Goosen M, Strehlau R, Gray GE, Kuhn L, Tiemessen CT
Assessment of an LSDV as an HIV vaccine vector for use in humans
Chapman R, van Diepen M, Douglass N, Galant S, Jaffer M, Margolin E, Ximba P, Hermanus T, Moore PL, Williamson A
Coordinated Fc-effector and neutralization functions in HIV-infected children define a window of opportunity for HIV vaccination
Nduati EW, Gorman MJ, Sein Y, Hermanus T, Oyaro I, Muema DM, Ndung’u T, Alter G, Moore PL
Data protection, data management, and data sharing: stakeholder perspectives on the protection of personal health information in South Africa
Ciara Staunton, Kathrina Tschigg, Gayle Sherman
Development and trial of a dried tube specimen (DTS) proficiency testing panel for dual HIV/syphilis rapid diagnostic tests
Maseko DV, Valashiya D, Kularatne RS
Dynamics of SARS-CoV-2 exposure in Malawian blood donors: a retrospective seroprevalence analysis between January 2020 and February 2021
Mandolo J, Msefula J, Henrion MYR, Brown C, Moyo B, Samon A, Moyo-Gwete T, Makhado Z, Ayres F, Motlou T, Mzindle N, Katala N, Muula A, Kwatra G, Msamala N, Likaka A, Mfune T, Moore PL, Mbaby B, French N, Heyderman RS, Swarthout TD, Jambo KC
Evaluation of the Aptima HIV-1 Quant Dx assay for HIV diagnosis at birth in South Africa
Aurélie Mukendi, Tendesayi Kufa, Gayle G Sherman, Karl-Günter Technau, Caroline T Tiemessen, Ahmad Haeri Mazanderani
FcγR genetic variation and HIV-1 vaccine efficacy: Context and considerations
Lassauniere R, and Tiemessen CT
Global phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis
Beale MA, Marks M, Cole MJ, Lee MK, Pitt R, Ruis C, Balla E, Crucitti T, Ewens M, Fernández-Naval C, Grankvist A, Guiver M, Kenyon CR, Khairullin R, Kularatne R, Arando M, Molini BJ, Obukhov A, Page EE, Petrovay F, Rietmeijer C, Rowley D, Shokoples S, Smit E, Sweeney EL, Taiaroa G, Vera JH, Wennerås C, Whiley DM, Williamson DA, Hughes G, Naidu P, Unemo M, Krajden M, Lukehart SA, Morshed MG, Fifer H, Thomson NR.
Lack of macrolide resistance in Mycoplasma genitalium infections in a cohort of pregnant women in South Africa
Peters RPH, Jung HS, Muller EE, Kock MM, Myer L, Klausner JD, Joseph Davey D.
Prior infection with SARS-CoV-2 boosts and broadens Ad26.COV2.S immunogenicity in a variant dependent manner
Keeton R, Richardson SI, Moyo-Gwete T, Hermanus T, Tincho MB, Benede N, Manamela NP, Baguma R, Makhado Z, Ngomti A, Motlou T, Mennen M, Chinhoyi L, Skelem S, Maboreke H, Doolabh D, Iranzadeh A, Otter A, Brooks T, Noursadeghi M, Moon J, Blackburn J, Hsiao N, Williamson C, Riou C, Gogo A, Garrett N, Bekker L, Gray G, Ntusi NAB, Moore PL, Burgers WA
Rapid and successful implementation of a Covid-19 convalescent plasma programme – the South African experience
Glatt TN, Hilton C, Nyoni C, Swarts A, Swaneveler R, Cowley J, Mmenu C, Moyo-Gwete T, Moore PL, Kutama M, Jaza J, Phayane I, Brits T, Koekemoer J, Jentsch U, Nelson D, van den Berg K, Vermeulen M.
Reduced CCR5 expression and immune quiescence in black South African controllers
Picton ACP, Paximadis M, Koor G, Bharuthram A, Shalekoff S, Lassauniere R, Ive P, and Tiemessen CT
Research priorities for a HIV cure
Deeks SG, Archin N, Cannon P, Collins S, Jones B, de Jong MAWP, Lambotte O, Lamplough R, Ndung’u T, Sugarman J, Tiemessen CT, Vandekerckhove, Lewin SR, on behalf of the IAS Global Scientific Strategy writing group.
SARS-CoV-2 exposure in Malawian blood donors: an analysis of seroprevalence and variant dynamics between January 2020 and July 2021
Jonathan Mandolo , Jacquline Msefula, Marc Y. R. Henrion, Comfort Brown , Brewster Moyo , Aubrey Samon , Thandeka Moyo-Gwete, Zanele Makhado, Frances Ayres, Thopisang Motlou, Nonkululeko Mzindle, Newton Kalata, Adamson S. Muula , Gaurav Kwatra, Natasha Nsamala, Andrew Likaka, Thom Mfune, Penny L. Moore, Bridon Mbaya, Neil French, Robert S. Heyderman, Todd Swarthout, and Kondwani C. Jambo.
The prevalence of unintended pregnancy and its association with HIV status among pregnant women in South Africa, a national antenatal survey, 2019
Selamawit Woldesenbet, Tendesayi Kufa, Carl Lombard Samuel Manda, Diane Morof, Mireille Cheyip, Kassahun Ayalew, Adrian Puren
Tuberculosis screening among ambulatory people living with HIV: a systematic review and individual participant data meta-analysis
Dhana A, Hamada Y, Kengne AP, Kerkhoff AD, Rangaka MX, Kredo T, Baddeley A, Miller C, Singh S, Hanifa Y, Grant AD, Fielding K, Affolabi D, Merle CS, Wachinou AP, Yoon C, Cattamanchi A, Hoffmann CJ, Martinson N, Mbu ET, Sander MS, Balcha TT, Skogmar S, Reeve BWP, Theron G, Ndlangalavu G, Modi S, Cavanaugh J, Swindells S, Chaisson RE, Ahmad Khan F, Howard AA, Wood R, Thit SS, Kyi MM, Hanson J, Drain PK, Shapiro AE, Kufa T, Churchyard G, Nguyen DT, Graviss EA, Bjerrum S, Johansen IS, Gersh JK, Horne DJ, LaCourse SM, Al-Darraji HAA, Kamarulzaman A, Kempker RR, Tukvadze N, Barr DA, Meintjes G, Maartens G.
Combinations of single chain variable fragments from HIV broadly 1 neutralizing antibodies demonstrate high potency and breadth
Van Dorsten RT, Wagh K, Moore PL, Morris L
Coverage of maternal viral load monitoring during pregnancy in South Africa: Results from the 2019 national Antenatal HIV Sentinel Survey
Woldesenbet S, Kufa-Chakezha T, Lombard C, Manda S, Cheyip M, Ayalew K, puren, A
Demographic and Behavioral Risk Factors Associated with Reduced Susceptibility of Neisseria gonorrhoeae to First-Line Antimicrobials in South African Men with Gonococcal Urethral Discharge
Ranmini S. Kularatne, Tendesayi Kufa, Lindy Gumede, Dumisile V. Maseko, David A. Lewis
Elicitation of neutralizing antibody responses to HIV-1 immunization with nanoparticle vaccine platforms
Murji MA, Qin JS, Hermanus T, Morris L, Georgiev IS
Eliminating HIV transmission through breast milk from women taking antiretroviral drugs
Goga AE, Van de Perre P, Ngandu N, Nagot N, Abrams EJ, Moodley D, King R, Molès JP, Chirinda W, Scarlatti G, Tylleskär T
Evaluating the performance of the GeneXpert HIV-1 qualitative assay as a consecutive test for a new early infant diagnosis algorithm in South Africa
Mukendi A, Kufa T, Murray T, Burke M, Strehlau R, Technau KG, Tiemessen CT, Sherman GG, Mazanderani AH
HIV broadly neutralizing antibodies expressed as IgG3 preserve neutralization potency and show improved Fc effector function
Richardson SI, Ayres F, Manamela NP, Oosthuysen B, Makhado Z, Lambson BE, Morris L, Moore PL. (2021)
In utero human cytomegalovirus infection is associated with increased levels of putatively protective maternal antibodies in nonprimary infection: evidence for boosting but not protection
Dorfman JR, Balla SR, Pathirana J, Groome MK, Madhi SA, Moore PL
Indeterminate HIV PCR results within South
Radebe L, Mazanderani AH, Sherman GG
Quality and turnaround times of viral load
Ngandu NK, Nsibande DF, Magasana V, Chirinda W, Mbira T, Sherman GG, Goga AE
Safety and Immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) Vaccine in People Living with and Without HIV: interim analysis of a randomised, double-blind, placebo-controlled phase 1b/2a trial in South Africa
Madhi SA, Koen AL, Izu A, Fairlie L, Cutland CL, Baillie V, Padayachee SD, Dheda K, Barnabas SL, Bhorat QE, Briner C, Aley PK, Bhikha S, Hermanus T, Horne E, Jose A, Kgagudi P, Lambe T, Masenya M, Masilela M, Mkhize NN, Moultrie A, Mukendi CK, Moyo-Gwete T, Nana AJ, Nzimande A, Patel F, Rhead S, Taoushanis C, Thombrayil A, van Eck S, Voysey M, Villafana TL, Vekemans J, Gilbert SC, Pollard AJ, Moore PL*, Kwatra G*, on behalf of the WITS VIDA COVID team
Therapeutic effect of CP-P59 against SARS-CoV-2 South African Variant
Ryu D, Song R, Kim M, Kim Y, Kim C, Kim J, Kwon K, Tijsma ASL, Nuijten PM, van Baalen CA, Hermanus T, Kgagudi P, Moyo-Gwete T, Moore PL, Choi YK, Lee S
Treponema pallidum Macrolide Resistance and Molecular Epidemiology in Southern Africa, 2008 to 2018
Johanna M E Venter, Etienne E Müller, Mahlape P Mahlangu, Ranmini S Kularatne
Ultrapotent antibodies against antigenically diverse and highly transmissible SARS CoV-2 variants
Wang L, Zhou T, Zhang Y, Yang ES, Schramm CA, Shi W, Pegu A, Oloninyi OK, Henry AR, Darko S, Narpala SR, Hatcher C, Martinez DR Tsybovsky Y, Phung E, Abiona OM, Antia A, Cale EM, Chang LA, Choe M, Corbett KS, Davis RL, DiPiazza AT, Gordon IJ, Hait SH, Hermanus T, Kgagudi P, Laboune F, Leung K, Liu T, Mason RD, Nazzari AF, Novik L, O’Connell S, O’Dell S, Olia AS, Schmidt SD, Stephens T, Stringham CD, Talana CA, Teng IT, Wagner D, Widge AT, Zhang B, Roederer M, Ledgerwood JE, Ruckwardt TJ, Gaudinski MR, Moore PL, Doria-Rose NA, Baric S, Graham BS, McDermott AB, Duek DC, Kwong PD, Mascola JR, Sullivan NJ, Misasi J
Cross-reactive neutralizing antibody responses elicited by SARS-CoV-2 501Y.V2 (B.1.351)
Moyo-Gwete T, Madzivhandila M, Makhado Z, Ayres F, Mhlanga D, Oosthuysen B, Lambson BE, Kgagudi P, Tegally H, Iranzadeh A, Doolabh D, Tyers L, Chinhoyi LR, Mennen M, Skelem S, Marais G, Bhiman JN, Ueckermann V, Rossouw T, Boswell M, de Oliveira T, Williamson C, Burgers WA, Ntusi N, Morris L, Moore PL
Diversity in immunogenomics: the value and the challenge
Peng K, Safonova Y, Shugay M, Popejoy A, Breden F, Brodin P, Burkhardt A, Bustamante C, Cao-Lormeau V, Corcoran MM, Duffy D, Guajardo MF, Fujita R, Greiff V, Jonsson VD, Liu X, Quintana-Murci L, Rossetti M, Xie J, Yaari G, Zhang W, Lees WD, Khatri P, Alachkar H, Scheepers C, Watson CT, Karlsson Hedestam GB, Mangul S.
Interleukin-8 genetic diversity, haplotype
Maria Paximadis, Anabela C.P. Picton, Dhriti Sengupta, Michele Ramsay , Adrian Puren, Caroline T. Tiemessen
Lack of association of KIR2DL1-R245 and KIR2DL1-C245 with HIV-1 control in black South Africans with HLA-C2
Shayne Loubser, Bianca Da Costa Dias , Sharon Shalekoff , Nikki L. Gentle , Caroline T. Tiemessen
Maternal HIV viral load testing during pregnancy and postpartum care in Gauteng Province, South Africa
F Moyo; A H Mazanderani,; T Kufa; G G Sherman
Normalization of B Cell Subsets but Not T Follicular Helper Phenotypes in Infants With Very Early Antiretroviral Treatment
Sharon Shalekoff , Shayne Loubser , Bianca Da Costa Dias , Renate Strehlau, Stephanie Shiau, Shuang Wang, Yun He, Elaine J. Abrams , Louise Kuhn and Caroline T. Tiemessen
Recent HIV infection among pregnant women in the 2017 antenatal sentinel cross-sectional survey, South Africa: Assay-based incidence measurement
Selamawit Woldesenbet, Tendesayi Kufa-Chakezha, Carl Lombard, Samuel Manda, Mireille Cheyip, Kassahun Ayalew, Brian Chirombo, Peter Barron, Karidia Diallo , Bharat Parekh , Adrian Puren
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Targeting Fc effector function in vaccine design
Richardson SI, Moore PL
The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations
Jorge E. B. da Rocha, Houcemeddine Othman, Gerrit Botha, Laura Cottino, David Twesigomwe, Samah Ahmed, Britt I. Drögemöller, Faisal M. Fadlelmola, Philip Machanick, Mamana Mbiyavanga, Sumir Panji , Galen E. B. Wright,
Clement Adebamowo, Mogomotsi Matshaba, Michéle Ramsay, Gustave Simo, Martin C. Simuunza, Caroline T. Tiemessen, Sandra Baldwin, Mathias Chiano, Charles Cox, Annette S. Gross, Pamela Thomas, Francisco-Javier Gamo and Scott Hazelhurst
Therapeutic effect of CP-P59 against SARS-CoV-2 South African Variant
Ryu D, Song R, Kim M, Kim Y, Kim C, Kim J, Kwon K, Tijsma ASL, Nuijten PM, van Baalen CA, Hermanus T, Kgagudi P, Gwete-Moyo T, Moore PL, Choi YK, Lee S
Virologic Response to Very Early HIV Treatment in Neonates
Stephanie Shiau, Renate Strehlau , Yanhan Shen , Yun He , Faeezah Patel , Megan Burke , Elaine J. Abrams , Caroline T. Tiemessen , Shuang Wang and Louise Kuhn
Achieving maternal viral load suppression for elimination of mother-to-child transmission of HIV in South Africa
Moyo, Faith; Mazanderani, Ahmad Haeri; Murray, Tanya; Sherman, Gayle G ; Kufa, Tendesayi
Efficacy of the ChAdOx1 nCoV-19 COVID-19 vaccine against the B.1.351 variant
Madhi SA, Baillie V, Cutland CL, Voysey M, Koen AL, Fairlie L, Padayhachee SD, Dheda K, Barnabas SL, Bhorat QE, Briner C, Kwatra G, NGS-SA, Wits-VIDA COVID team, Ahmed K, Aley P, Bhika S, Bhiman JN, Bhorat AE, du Plessis J, Ismail A, Groenewald M, Horne E, Hwa S, Jose A, Lambe T, Laubscher M, Malahleha M, Masenya M, Masilela M, , McKenzie S, Molapo K, Moultie A, Oelofse S, Patel F, Pillay S, Rhead S, Rodel H, Rossouw L, Taoushanis C, Tegally H, Thombrayil A, van Eck S, Wibmer CK, Durham NM, Kelly EJ, Villafana TL, Gilbert S, Pollard AJ, de Oliveira T, Moore PL, Sigal A, Izu A.
Estimating the contribution of key populations towards HIV transmission in South Africa
Jack Stone , Christinah Mukandavire, Marie-Claude Boily, Hannah Fraser , Sharmistha Mishra,Sheree Schwartz, Amrita Rao, Katharine J Looker , Matthew Quaife , Fern Terris-Prestholt,Alexander Marr, Tim Lane , Jenny Coetzee, Glenda Gray, Kennedy Otwombe, Minja Milovanovic, Harry Hausler, Katherine Young, Mfezi Mcingana, Manezi Ncedani, Adrian Puren, Gillian Hunt,Zamakayise Kose, Nancy Phaswana-Mafuya, Stefan Baral and Peter Vickerman
False-positive rapid diagnostic tests in paediatric and obstetric patients in South Africa
Keal J, Mazanderani AH, van Dongen N, Sorour G, Technau K-G
Human whole genome sequencing in South Africa
Glanzmann B, Jooste T, Ghoor S, Gordon R, Mia R, Mao R, Charls P, Doumann C, Kotze M, Peeters A, Esser M, Tiemessen CT, Wilkinson RJ, Louw J, Gray G, Warren RM, Moller M, Kinnear C.
Infection of Chinese rhesus monkeys with a subtype C SHIV resulted in attenuated in vivo viral replication despite successful animal-to-animal serial passages
Chege GK, Adams CH, Keyser AT Bekker V, Morris L, Villinger FJ, Williamson A, Chapman RE.
In utero human cytomegalovirus infection is associated with increased levels of putatively protective maternal antibodies in nonprimary infection: evidence for boosting but not protection
Dorfman JR, Balla SR, Pathirana J, Groome MK, Madhi SA, Moore PL.
Low Pretreatment Viral Loads in Infants With HIV in an Era of High-maternal Antiretroviral Therapy Coverage
Patel F, Shiau S, Strehlau R, Shen Y, Burke M, Paximadis M, Shalekoff S, Schramm D, Technau KG, Sherman GG, Coovadia A, Tiemessen CT, Abrams EJ, Kuhn L
Modified adenovirus prime-protein boost clade C HIV vaccine strategy results in reduced viral DNA in blood and tissues following Tier 2 SHIV challenge
Malherbe D, Vang L, Mendy J, Barnette PT, Spencer D, Reed JS, Kareko BW, Sather N, Pandey S, Wibmer CK, Robins H, Fuller D, Park B, Lakhashe SK, Wilson JM, Axthelm MK, Ruprecht RM, Moore PL, Sacha JB, Hessell AJ, Alexander J, Haigwood NL. (2021)
Modifications to the HIV-1 SAAVI MVA-C vaccine improve in vitro expression and in vivo immunogenicity
Douglass N, Van Diepen M, Chapman R, Galant S, Margolin E, Ximba P, Hermanus H, Moore PL, Williamson A.
Paediatric & Adolescent HIV Viral load Monitoring, 2014-2020
Mazanderani AH, Sherman GG.
SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma
Wibmer CK, Ayres F, Hermanus T, Madzivhandila M, Kgagudi P, Lambson BE, Marion Vermeulen M, van den Berg K, Rossouw T, Boswell M, Ueckermann V, Meiring S, von Gottberg A, Cohen C, Morris L, Bhiman JL, Moore PL.
Trends in RPR Seropositivity among Children Younger than 2 Years in South Africa, 2010–2019
Mathebula R, Kuonza L, Musekiwa A, Kularatne R, Puren A, Reubenson G, Sherman G, Kufa T.
Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition
Corey L, Gilbert PB, Juraska M, Montefiori DC, Morris L, Karuna ST, Edupuganti S, Mgodi NM, deCamp AC, Rudnicki E, Huang Y, Gonzales P Cabello R, Orrell C, Lama JR, Laher F, Lazarus EM, Sanchez J, Frank I, Hinojosa J, Sobieszczyk ME, Marshall KE, Mukwekwerere PG, Makhema J, Baden LR, Mullins JI, Williamson C, Hural J, McElrath MJ, Bentley C, Takuva S, Lorenzo MMG, Burns DN, Espy N, Randhawa AK, Kochar N, Piwowar-Manning E, Donell DJ, Sista N, Andrew P, Kublin JG, Gray G, Ledgerwood JE, Mascola JR, Cohen MS on behalf of the HVTN 704/HPTN 085 and HVTN 703/HPTN 081 Study Teams. (2021)
