Special Publications are to help the public understand important information about communicable diseases. The NICD produces a number of topically themed publications on communicable diseases that are of public health importance.  These special publications can be freely downloaded below. 

South Africa is committed to attaining the UNAIDS 909090 targets to control the HIV epidemic through quality comprehensive health services and use of highly effective antiretroviral treatment (ART). The principal goal of ART is to attain and maintain viral suppression, which will decrease morbidity and mortality from HIV as well as improve the quality of life for clients living with HIV.

The 2019 HIV clinical guidelines have been revised to include a new formulation of the fixed dose combination (FDC) of Tenofovir (TDF) 300 mg + Lamivudine (3TC) 300 mg + Dolutegravir (DTG) 50 mg (TLD) for all eligible adults, adolescents and children over the age of 10 years and weighing 35 kg or more.

ART Clinical guidelines for the management of HIV  (2019)

Candida auris is an invasive healthcare-associated fungal pathogen. Cases of candidemia, defined as illness in patients with Candida cultured from blood, were detected through national laboratory-based surveillance in South Africa during 2016–2017.

Epidemiologic Shift in Candidemia Driven by Candida auris, South Africa, 2016–2017 (2019)

Guidelines for the Prevention of Transmission of Communicable infections from mother to child (HIV, Hepatitis, Listeriosis, Malaria, Syphilis and TB).

While the WHO calls for dual elimination of HIV and syphilis, South Africa aspires to eliminate all infections that are transmittable from mother to child by promoting the prevention of such infections, early diagnosis and proper management in order to reduce maternal, neonatal and child morbidity and mortality.


South Africa has been implementing the national antenatal sentinel HIV prevalence survey since 1990. The 2022 edition of the survey was primarily focused on determining the geographical distribution and pattern of HIV sero-prevalence among pregnant women aged 15- 49 years, attending public ANC clinics in South Africa at national, provincial and district level. 

 National Antenatal Sentinel HIV Survey Key Findings, South Africa (2022)

This survey aimed to assess the utility of routine prevention of mother-to-child transmission of HIV (PMTCT) program data for HIV sentinel surveillance amongst pregnant women.


As part of the new National Aetiology Surveillance Programme of sexually transmitted infections (STIs), laboratory-based STI surveillance was undertaken in 36 Primary Health Clinics (PHCs) across nine South African provinces. The main objectives of the survey were to determine the microbial aetiologies of the three major STI syndromes, as well as the prevalence of HPV infection and individual genotypes among a sample of adolescent girls and young women accessing family planning services. Secondary objectives included determination of the prevalence of serologicallydiagnosed co-infections: syphilis, infectious hepatitis B, and herpes simplex virus type 2 (HSV-2) among patients presenting with STI syndromes. Additionally, prevalence of human immunodeficiency virus (HIV) infection among STI patients and family planning clinic participants was ascertained.

Sentinel Surveillance of STI Syndrome aetiologies and HPV genotypes

This booklet has information regarding the vaccines your child/children will get at each stage of their development. We have also included workpages so that you can remind yourself when they will be due for their next vaccination. It includes answers to some frequently asked questions and misconceptions about vaccines as well as links to where you can find further reliable information.